Course Overview
Jaw necrosis, an increasingly recognized clinical challenge, encompasses a spectrum of conditions that result in the localized death of bone tissue within the jaws. With the expanding use of antiresorptive and antiangiogenic agents, as well as improved cancer survival rates, dental and medical practitioners are encountering medication-related and radiation-induced jaw necrosis with greater frequency. Jaw necrosis can present significant morbidity, have a profound impact on patients’ quality of life, and often requires complex multidisciplinary management.
Understanding the epidemiology, underlying pathophysiology, and varied risk factors associated with jaw necrosis is critical for prevention and early diagnosis. The condition may arise from diverse etiologies—including drug therapy (notably bisphosphonates and denosumab), radiation for head and neck cancers, or trauma. Patient comorbidities, oral hygiene, dental procedures, and systemic health all contribute to susceptibility and prognosis. As an increasing number of patients present with histories that predispose them to osteonecrosis, evidence-based approaches to risk assessment, dental management, and patient counseling become essential in clinical practice.
This course offers a comprehensive examination of jaw necrosis, guiding participants through classification, risk identification, clinical diagnosis, prevention, and both medical and surgical management strategies. Upon completion, practitioners will be equipped with the tools to minimize risk, recognize early signs, coordinate multidisciplinary care, and optimize outcomes for affected patients.
Learning Objectives
After completing this course, participants will be able to:
- Define jaw necrosis and distinguish between its major types and classifications.
- Summarize the epidemiology, etiologies, and predisposing risk factors for jaw necrosis.
- Describe the pathophysiologic mechanisms underlying medication- and radiation-induced osteonecrosis of the jaw.
- Evaluate and identify patients at increased risk using clinical and dental screening protocols.
- Apply evidence-based diagnostic criteria and staging systems in clinical assessment.
- Implement preventive measures and coordinate care before, during, and after at-risk therapies.
- Discuss medical, surgical, and adjunctive treatment strategies, including patient-specific considerations.
- Manage follow-up, monitor outcomes, and provide supportive long-term care to optimize quality of life.
- Critically review emerging research and anticipate future advances in the management of jaw necrosis.